Inflammation and osteoclasts
نویسندگان
چکیده
منابع مشابه
Muscle paralysis induces bone marrow inflammation and predisposition to formation of giant osteoclasts.
Transient muscle paralysis engendered by a single injection of botulinum toxin A (BTxA) rapidly induces profound focal bone resorption within the medullary cavity of adjacent bones. While initially conceived as a model of mechanical disuse, osteoclastic resorption in this model is disproportionately severe compared with the modest gait defect that is created. Preliminary studies of bone marrow ...
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AIM To investigate the hypothesis that complement mediates the recruitment of mononuclear osteoclast precursors to the exposed mineralised bone surface. METHODS Synthetic hydroxyapatite was incubated in vitro with fresh human serum, with and without complement activation inhibitors. Assays for complement components and the generation of the C3 breakdown product C3d were done. C3 deposition in...
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ژورنال
عنوان ژورنال: Japanese Journal of Clinical Immunology
سال: 2017
ISSN: 0911-4300,1349-7413
DOI: 10.2177/jsci.40.367